Building Model of DNA, RNA, and Protein Synthesis ~ Biodayu

Building Model of DNA, RNA, and Protein Synthesis

1.1. Goal

f To study DNA, RNA, and protein synthesis using models

1.2. Basic Theories.

1.3. Tools and Materials

a. Tools

j Toothpick or matches

j Plasticine in 8 colors

Note : other materials may be used, such as color papers, markers, scissors, and glue.

b. Materials

b ….

1.4. Working Procedure

Make a three- or two-dimensional model as follows.

· DNA molecular structure

Make a model that shows the double-helix configuration of deoxyribose, phosphate and bases of DNA.

· DNA replication

Make a short model of DNA (about 10 nucleotides). Then make the replication model.

· mRNA formation

Build the transcription mechanism of DNA into mRNA by determining the DNA template.

· Control of mRNA on protein synthesis

Build models of amino acids, tRNA, and short chain of mRNA. Show how translation on the base sequence of mRNA into protein is done.

· Ribosome work

Make two ribosome models. Move them along the chain of mRNA to show translation and its product of polypeptide chain.

Write down the working procedure explained by your teacher in the column below !

1.5. Observation Result (materials may be used, such as color papers, markers, color pencils)

a. short model of DNA (about 10 nucleotides)

b. The replication model.

c. Build the transcription mechanism of DNA into mRNA by determining the DNA template.

1.6. Questions

1. Why does translation occur in ribosome?

2. Write down the different components of DNA and RNA.

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